Reka li-Peptides

Fumana BPC 157 10Vials [5mg / 1Vial] - Peptides
Lebokose la 10Vials, 5mg / vial. Kakaretso 50mg BPC 157

Pentadecapeptide BPC 157, e entsoeng ka li-amino acid tse 15, ke tatellano e sa fellang ea motsoako oa tšireletso ea 'mele (BPC) o sibolloang le o arohaneng le lero la mala a motho. Ka liteko ho 'nile ha bontšoa ho potlakisa pholiso ea maqeba a mangata a fapaneng, ho akarelletsa le transected rat Achilles tendon. Phuputso ena e ne e etselitsoe ho batlisisa mokhoa o ka bang teng oa BPC 157 ho ntlafatsa pholiso ea tendon e lemetseng. Ho ile ha hlahlojoa ho hlaha ha li-tendon fibroblasts tse tsoang ho li-tendon tse hlahisitsoeng ka BPC 157 kapa ntle le tsona. Liphello li bontšitse hore BPC 157 e potlakisitse haholo ho hōla ha li-tendon explants. Ho ata ha lisele tsa li-tendon fibroblasts tse hlahisitsoeng ho rat Achilles tendon ha lia ka tsa ameha ka ho toba ke BPC 157 joalokaha ho hlahlojoa ke MTT assay.

Leha ho le joalo, ho pholoha ha lisele tse tšoaroang ke BPC 157 ho ile ha eketseha haholo tlas'a khatello ea H2O2. BPC 157 e ekelitse ho falla ha in vitro ea tendon fibroblasts ka mokhoa o itšetlehileng ka lethal dose joalokaha ho senotsoe ke transwell filter migration assay. BPC 157 e boetse e potlakisa ho ata ha li-tendon fibroblasts ho itšetlehile ka tekanyo ea lijana tsa setso. Sebopeho sa F-actin joalokaha se hlokometsoe ke FITC-phalloidin staining se ile sa kenngoa ho BPC 157-treated fibroblasts. Polelo ea protheine le ts'ebetso ea FAK le paxillin li khethiloe ke tlhahlobo ea blot ea Bophirimela, 'me maemo a phosphorylation a FAK le paxillin a ile a eketseha ho itšetlehile ka tekanyo ea BPC 157 ha kakaretso ea protheine e sa fetoloa.

Qetellong, BPC 157 e khothalletsa ex vivo outgrowth ea tendon fibroblasts ho tloha ho li-tendon explants, ho phela ha lisele tlas'a khatello ea kelello, le ho falla ha in vitro ea tendon fibroblasts, eo ho ka etsahalang hore e kene lipakeng ke ts'ebetso ea FAK-paxillin tsela.

Tlhokomeliso: E kopanye le Bacteriostatic Water (ha e kenyelelitsoe)